DNA Replication

Question 1

DNA Polymerase III

Answer 1

5-3 synthesis

Exonuclease 3-5 proofreads

Question 2

DNA TOPOISOMERASE

Answer 2

Creates a single or double stranded break in the helix to add or remove supercoils.
Topoisomerase inhibitors
-fluoroquinolonas
-prok topoiso II (DNA gyrase) and Toposiso IV Etoposide/teniposide
Euk topoiso II

Question 3

DNA Polymerase I

Answer 3

Remplaza RNA primer por DNA

Also same function as DNA polymerase III but also excises RNA primer with 5-3 exonuclease

Question 4

Primase

RNA polymerase

Answer 4

Synthesis of RNA primer