USMLE > Pathology > Flashcards
➰ 1 antitrypsin
Affects 🌬 & 🏈
Misfolded gene product protein aggregates in hepatocellular ER➡️ cirrhosis with PAS ➕
Lungs ⬇️ antitrypsin uninhibits elastase in alveoli ➡️ ⤵️elastic tissue↪️panacinar enphysema