doxycycline

Question 1

doxycycline group

Answer 1

tetracycline

Question 2

doxycycline moa

Answer 2

• inhibits protein synthesis by binding to 30 s ribosome in susceptible organism
• primarily bacteriostatic

Question 3

doxycycline uses

Answer 3

• empirical therapy
• venereal disease such as chlamydia and lymphogranuloma venerum
• atypical pneumonia
• cholera
• brucellosis
• plaque
• relapsing fever
• in pts allergic to penicillin
• acne vulgaris

Question 4

doxycycline A/E

Answer 4

• epigastric pain, n/v
• odynophagia, esophageal ulceration
• jaundice
• phototoxicity
• brown discoloration, ill formed teeth (susceptibility to caries)
• if given during pregnancy or childhood, suppression of bone growth
• diabetes insipidus
• superinfection

Question 5

doxycycline c/i

Answer 5

• pregnancy, lactation and childhood
• should be avoided with diuretics increase blood urea level
• should not be mixed with penicillin iv