Endochondral Ossification

Question 1

Step 1

Answer 1

Enlargement of hyalin cartilage model by chondroblasts.

Question 2

Step 2:

Answer 2

Invasion of perichondrium by blood vessels; transforms into periosteum

Question 3

Step 3:

Answer 3

cartilage model invaded by blood vessels and osteoblasts from the periosteum establishing “ossification centers”

Question 4

Step 4:

Answer 4

calcification of cartilage creates trabeculae, which causes death of cartilage cells (chondrocytes)

Question 5

Step 5

Answer 5

surface of osteoblasts form compact bone against inner surface of periosteum

Question 6

Step 6

Answer 6

breakdown of bone matrix by osteoclasts creates a hollow cavity for red and yellow marrow.

Question 7

step 7

Answer 7

lengthwise growth occurs at “epiphyseal cartilage plate”