Where does the endocrine system secrete hormones?
Into the blood system
What biomolecule are most hormones?
Proteins
What biomolecules are some hormones, e.g steroids
Lipids
Difference between the exocrine and endocrine glands
An exocrine gland releases its product into ducts (e.g salivary, sweat glands)
While an endocrine gland releases hormones directly into the bloodstream
What is both an exocrine and endocrine gland?
The pancreas
Hormone
Chemical messenger
Pituitary gland - location - hormone - function
Beneath brain
Growth hormone
Bone elongation
Hypothalamus - location - hormone - function
Base of brain, above pituitary
ADH (Anti-diuretic hormone)
Water reabsorption in the kidneys (osmoregulation)
Pineal - location - hormone - function
Within brain
Melatonin
Controls body rhythms (circadian rhythm)
Thyroid - location - hormone - function
On trachea- in neck
Thyroxine (tyrosine + iodine)
Controls metabolism
Deficiency in thyroxine
Children = cretinism , symptom is low metabolism
Adult = myxoedema, symptom is tired+weight gain - extreme case is goitre
Corrective measure for thyroxine deficiency
Thyroxine or iodine tablets
Excess in thyroxine
Grave’s disease - increased metabolism, bulging eyes, hungry, weight loss
Corrective measure for excessive thyroxine
Corrected by surgery or radiation
Parathyroids - location - hormone - function
In the thyroid gland - parathormone - controls release of calcium from bones into plasma
Thymus - location - hormone - function
Top of chest(thoracic cavity) - thymosin - matures lymphocytes
adrenals - location - hormone - function
Top of kidneys - adrenaline - flight/fight response
Pancreas - location - hormone - function
Abdomen/below stomach - insulin - reduces blood sugar levels
Pancreatic endocrine function
Insulin produced by islets of langerhans
Pancreatic exocrine function
Secretes digestive enzymes e.g protease
Two examples of hormone supplements and what they do
Insulin - helps diabetics (controls glucose levels in blood)
Anabolic steroids - builds protein
Negative feedback loop; thyroxine
Low thyroxine - TSH is released from pituitary gland - negative inhibition stops too much thyroxine being produced