Pathogen
Disease causing organism
Examples of the first line of defence
Skin
Clotting
Mucus
What is in the second line of general defence
Phagocytes
Inflammation
Phagocytes
Small WBCs that surround engulf microorganisms
Macrophages
Large phagocytes
Some are scavengers
Others remain in lymphatic organs
Defence proteins
Interferons attach viruses
Inflammation
More white blood cells come to infected area
Swelling, redness, heat
Whole body= fever - stops bacterial and viral reproduction
Induced immunity
Using antibodies to resist specific pathogens
Immunisation
When we produce or are injected with antibodies against a pathogen
Vaccine
A non-disease causing dose of a pathogen which triggers the production of antibodies
2 types of induced immunity
Active and passive
Each can be artificial or natural
Natural active immunity
Pathogens from environment
Artificial active immunity
Vaccine
Active immunity
Antibodies produced in the body
Passive immunity
Antibodies entering the body
Natural passive immunity
Breast milk
Placenta
Artificial passive immunity
Injection e.g tetanus
Where are lymphocytes formed
Bone marrow
Where are lymphocytes active
Lymphatic tissue
What types of cells can lymphocytes be
B cells or T cells
Where do B cells mature
Bone marrow
Where do T cells mature
Thymus
Four types of T cells
Helper
Killer
Suppressor
Memory
Suppressor T cell role
Turn of immune response