Enteric Nervous System

Question 1

neurons and glial cells of ENS are derived from…

Answer 1

neural crest

Question 2

IPAN

Answer 2

Intrinsic primary afferent neurons

project from submucosal plexus to myenteric plexus

Question 3

where is the submucosal plexus found?

Answer 3

large and small intestine

Question 4

where is the myenteric plexus?

Answer 4

b/t inner circular layer and outer longitudinal layer - throughout GI tract

Question 5

Interstitial cells of cajal

Answer 5

pacemaker cells of the gut - located in muscular layers of GI tract, mostly in greater curvature

Question 6

causes of nausea and vomiting

Answer 6

• INFECTIONS!!!
• toxins
• metabolic disorders
• CNS disorders
• oculovestibular disorders
• pregnancy
• medications

Question 7

common causes of chronic nausea and vomiting

Answer 7

• gastroparesis
• intestinal pseudo-obstruction
• psychogenic

Question 8

areas of GI tract affected by scleroderma

Answer 8

loss of SM

• esophagus most common
• small intestine next
• NOT stomach

Question 9

Normal colonic motor patterns

Answer 9

• Low amplitude contractions: short distances
• High amplitude propagating contractions: longer distances, assoc w/ defecation