SBM IV GI > IBD > Flashcards

IBD Flashcards

(25 cards)

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1
Q

distinguishing features b/t UC and Crohn’s disease

A
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2
Q
A

ulcerative colitis

  • crytabcesses, cryptitis = chronic inflammation
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3
Q

differences in age and sex distrib in UC and Crohn’s

A

more males have Crohn’s, similar age distrib (highest onset rate in 20s-30s)

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4
Q

genetic susceptibility - which has more, Crohn’s or UC?

A

Crohn’s! much higher twin concordance

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5
Q

environmental risk factors for crohn’s and UC

A

​smoking: protective in UC, risk in Crohn’s

appendectomy protective for UC

high sanitation level in childhood - risk for CD

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6
Q

UC - distribution of disease

A
  • colon only
  • continuous distribution
  • rectal involvement
  • mucosal inflammation
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7
Q

sx of UC

A
  • rectal bleeding (hematochezia)
  • diarrhea
  • abdominal pain
  • tenesmus and urgency
  • systemic sx: fever, night sweats
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8
Q
A

Crohn’s: nodulatiry, ulceration, exudate, luminal narrowing

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9
Q

complications of UC

A
  • hemorrhage
  • toxic megacolon
  • perforation
  • colon cancer
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10
Q

lympocytic colitis

A
  • a type of microscopic colitis
  • watery diarrhea
  • occurs in middle age adults, M =F
  • normal endoscopy, but inflammation on microscopic level
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11
Q

collagenous colitis

A

type of microscopic colitis

  • watery diarrhea but no bleeding
  • predominantly older women
  • normal endoscopy but inflammation on microscopic level
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12
Q

Crohn’s disease distribution and distinguishing feature

A
  • transmural inflammation
  • granulomas
  • strictures
  • skip lesions
  • can have small bowel involvement
  • rectal sparing
  • perineal disease
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13
Q
A

Crohn’s

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14
Q
A

non-caseating granuloma in Crohn’s

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15
Q

Crohn’s clinical patterns

A
  • inflammation: pain, tenderness, diarrhea, low-grade fever, weight loss
  • confined perforation: mimics appendicitis (ileum), mimics diverticulitis (sigmoid colon)
  • obstruction: cramps, distension, borborygmi, vomiting
  • fistulization: to anywhere
  • perineal complications
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16
Q

childhood presentations of IBD

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A
  • fever
  • anemia
  • arthritis
  • failure of growth and development
17
Q
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A

apthous stomatitis - assoc w/ IBD

18
Q

skin conditions assoc w/ IBD

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A
  • erythema nodosum: more w/ Crohn’s
  • pyoderma gangrenosum: more w/ UC
19
Q

extraintestinal manifestations of IBD

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A
  • aphthous stomatitis
  • episcleritis and uveitis
  • arthritis
  • vascular complications
  • skin: e. nodosum, p. gangrenosum
  • hepatobiliary: primary sclerosing cholangitis
20
Q
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A

primary sclerosiing cholangitis - assoc w/ IBD

21
Q

ddx IBD vs IBS

22
Q
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A

crypt abcesses in ACUTE (INFECTIOUS) COLITIS

*architecture intact (unlike UC)

23
Q
24
Q
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A

crypt abscess

25
thumbprinting - sign of UC intestinal complication of dissection through wall of colon --\> serositis and paralytic ileus
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