Example MCQs Set 2

Question 1

1. Correctly list major lipoproteins in order from largest to smallest:
   a. VLDL, chylomicrons, IDL, HDL, LDL
   b. Chylomicrons, VLDL, IDL, HDL, LDL
   c. VLDL, IDL, chylomicrons, LDL, HDL
   d. Chylomicrons, VLDL, IDL, LDL, HDL

Answer 1

d. Chylomicrons, VLDL, IDL, LDL, HDL

Question 2

2. What is the calculated non-HDL cholesterol for a patient with the following lipid values: total cholesterol=226 mg/dL, HDL cholesterol=37 mg/dL, and triglycerides=113 mg/dL?
   a. 76 mg/dL
   b. 189 mg/dL
   c. 166 mg/dL
   d. 150 mg/dL

Answer 2

b. 189 mg/dL

Question 3

3. Cholesterol is essential for the normal functioning of an organism because it is:
   a. an essential component of all cell membranes
   b. the major component of chylomicrons
   c. a precursor of all steroid hormones
   d. the major gluconeogenic substrate of the liver
   e. a,b,c are correct
   f. a and c are correct

Answer 3

f. a and c are correct

Question 4

For a patient who has an elevated Lp(a), the abnormality most likely to be detected by a basic lipid panel is:
a. elevated VLDL cholesterol
b. low HDL cholesterol
c. elevated LDL cholesterol
d. elevated fasting triglycerides

Answer 4

c. elevated LDL cholesterol

Question 5

5. Lipoprotein particles are classified primarily according to their:
   a. density
   b. protein composition (% by weight)
   c. migration pattern in agarose gel
   d. site of synthesis
   e. a,b,c are correct
   f. a and c are correct

Answer 5

f. a and c are correct

Question 6

1. Which of the following patient groups may benefit the most from direct measurement of FT4?
   a. pregnant women
   b. females going through puberty
   c. overweight individuals
   d. elderly patients
   e. none of the above

Answer 6

a. pregnant women

Question 7

2. Which of the following statements regarding laboratory testing for thyroid function is incorrect?
   a. currently, most laboratories utilize immunoassays for measuring serum TSH
   b. interferences in TSH immunoassays are uncommon
   c. the recommended screening test for thyroid conditions in high-risk populations is TSH
   d. TSH receptor antibodies are increased in Graves’s disease

Answer 7

b. interferences in TSH immunoassays are uncommon

Question 8

3. Which of the following thyroid autoantibodies is most commonly found in patients with Hashimoto’s thyroiditis?
   a. thyroglobulin (Tg) antibodies
   b. thyroid-stimulating immunoglobulins
   c. thyroid peroxidase (TPO) antibodies
   d. thyroid stimulating hormone receptor (TSHR) antibodies
   e. thyroid-binding inhibitory immunoglobulins

Answer 8

c. thyroid peroxidase (TPO) antibodies

Question 9

4. The primary serum test to screen for thyroid disease is
   a. Free T4
   b. Total T4
   c. Autoimmune antibodies to thyroid tissue
   d. TSH
   e. Free T3

Answer 9

d. TSH

Question 10

5. All of the statements about iodine are true EXCEPT:
   a. Iodine deficiency is one of the most common causes of hypothyroidism in the world
   b. Iodine deficiency is particularly important in pregnancy
   c. Iodine deficiency can lead to goitre and cretinism
   d. Excess iodine can damage normal thyroid

Answer 10

d. Excess iodine can damage normal thyroid