Fibromyalgia

Question 1

how prevalent/costly is FMS

Answer 1

~2-5% of population. Costs as much as OA

Question 2

three conditions for diagnosis

Answer 2

widespread pain >=7 and symptom severity >=5; symptoms for at least 3 months; no other explanation

Question 3

main FMS symptoms

Answer 3

systemic pain, fatigue, unrefreshing sleep

Question 4

what are the three FDA approved drugs

Answer 4

milnacipran and duloxetine (SNRIs), pregabalin “lyrica” (GABA agonist)

Question 5

dosing of lyrica

Answer 5

75 mg BID

Question 6

dosing of duloxetine

Answer 6

60 mg QD (30 for first week)

Question 7

first line of treatment

Answer 7

improve sleep and lifestyle factors