anorexia nervosa
restricting type
- low body weight due to restricting
energy intake and/or excessive exercise only
binge-eating/purging type
- low body weight due to a pattern of eating large amounts of food followed by self-induced vomiting, misuse of
laxatives, etc.
bulimia nervosa
pattern of binge eating
Compensatory behaviours in response to binge eating in order to prevent weight gain
- vomiting, misuse of laxatives, fasting, excessive exercise, etc.
binge-eating disorder
Pattern of binge eating:
- eating large amounts of food in discrete periods of time
- feeling lack of control over eating during these periods
Binge-eating episodes are associated with 3 (or more) of:
- eating very rapidly.
- eating until feeling uncomfortably full
- eating large amounts of food when not hungry
- eating alone due to feeling embarrassed by how much is eaten
- feeling disgusted with oneself, depressed, or very guilty
avoidant/restrictive food intake disorder
lack of interest in or avoidance of food leading to inadequate nutritional/ energy intake
- seen in people with autism
unspecified feeding or eating disorder
sx of an eating disorder cause significant distress or impairment to functioning in daily life but do not meet the full criteria for any of the other eating disorders
catabolism
breakdown of compounds to release energy
anabolism
building compounds
- uses energy
factors influencing energy requirements
energy imbalance
- feasting
more energy is consumed than expended
excess nutrients stored as…
excess CHO
- stored first as glycogen (limited)
- then stored as fat
excess fat
- immediately routed to adipose tissue
excess protein
- possesses enzymes to convert excess protein to body fat (very inefficient)
energy imbalance
– fasting
glycogen used first
- glucose from glycogen stores
- fatty acids from adipose tissues
- glucose needed for brain
- brain, nerves, and RBC cannot metabolize fatty acids
protein breakdown & ketosis
- breakdown = glucose for brain
- ketone body production ↑as fast continues
- lean tissue wasting slows but continues
slowed metabolism
- conserves fat and lean tissue
ketone bodies
acidic, water-soluble compounds produced by the liver from fatty acid fragments
- alternative energy source; can lead to ketoacidosis (bad)
time frame for fasting
12-15 hrs
- glycogen stores run out
12/15-48 hrs
- protein is main source of energy (90%)
- muscle breakdown (75-100g/d)
>48hrs
- body shifts to energy mostly from ketone bodies
- basal metabolic rate declines
- slow steady muscle loss
hazards of fasting
energy balance
energy in (kcal) - energy out
energy out:
- basal metabolism
- energy for physical activities
energy to manage food
basal metabolism
~2/3 of a sedentary person’s expenditure
Measurements: basal metabolic rate (BMR) and resting metabolic rate (RMR)
components of energy expenditure
basal = 50-65%
physical activity = 30-50%
thermic effect of food = 10%
estimated energy requirements
Dependent upon age, gender, weight, height, and physical activity
↑or↓ BMR
Fasting/starvation, malnutrition
Hormones
Smoking, caffeine
Sleep
Age, gender
Height, growth, body composition
Fever
Stress, environment
hormones involved in weight loss/gain (important!)
leptin
- suppresses appetite and promotes efficient energy storage
- obese people are leptin resistant
ghrelin
- stimulates appetite and promotes efficient energy storage
Lipoprotein lipase (LPL)
Cell surface enzyme that hydrolyzes tris and promotes fat storage
Higher level of LPL activity in fat cells of obese people
- makes fat storage efficient
recommendations for SAFE weight loss
individualized
- should integrate healthy eating patterns, physical activities, supportive environments, and psychosocial support
- small changes, moderate and sustained losses, and reasonable goals
- refer to dietician
recommendations for SAFE weight gain
-physical activity to build muscles
- energy-dense foods
- 3 meals daily
- large portions + snacks
- juice and milk
> ↑kcals w/ beverages
what does ozempic do?
Ozempic mimics Glp1 hormone
= suppress appetite and digestion