Pharmacy Stage 1 > Functional group amides > Flashcards

Functional group amides Flashcards

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1
Q

carbonyl compounds are substituted by an atom…….. electronegative than carbon

A

electronegative

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2
Q

Stability

A

unreactive

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3
Q

are they more stable or less stable than esters

A

more

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4
Q

what stabilises it through resonance

A

N lp

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5
Q

pka

A

35

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6
Q

….. e- are shared between ….. …. orbitals

A

4
3
pie

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7
Q

nitrogen is …….. in p orbital

A

planar

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8
Q

N is what hybridisation

A

sp2

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9
Q

greater …….. density in oxygen

A

electron

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10
Q

can they be cis/trans

A

yes

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11
Q

rate of rotation ….. in ………. polar solvent

A

fastets

least

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12
Q

water/DMSO have

A

strong dipole moment

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13
Q

acid chlorides are made of

A

several reagents

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14
Q

two ways of making direct amide formation

A

ester

acid

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Pharmacy Stage 1
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