Glomerular filtration

Question 1

What is the filtration fraction?

Answer 1

1. % of renal plasma flow that is filtered at the glomerulus

Question 2

How is sodium reabsorbed?

Answer 2

1. Electrochemical gradient 2. Secondary active transport 3. Na-H antiporter 4. Na-K ATPase (tubule cell to interstitium)

Question 3

How is glucose reabsorbed?

Answer 3

1. Into cell via secondary active transport (Na-gluc) 2. Facilitated diffusion (tubule cell to interstitium)

Question 4

How is water reabsorbed?

Answer 4

Isosmotic reabsorption in proximal tubule as a result of solute (NaCl, glucose, amino acid) reabsorption

Question 5

Why is the threshold maximum for glucose lower than the transport maximum for glucose?

Answer 5

Not all tubules have the same transport maximum

Question 6

What is osmotic diuresis?

Answer 6

Un-reabsorbed glucose in the urine decreases water reabsorption, lowering the sodium concentration in the tubule