Pulmonary circulation

Question 1

What are the main mechanisms of sustained pulmonary arterial hypertension?

Answer 1

Persistent hypoxic vasoconstriction and the associated vascular structural remodeling

Question 2

Where is blood flow greatest in the lungs?

Answer 2

Base

Question 3

How is interstitial fluid pressure in the lungs compared to that in the peripheral subcutaneous tissue?

Answer 3

Interstitial fluid pressure in the lungs is slightly more negative

Question 4

What is the normal value for V/Q (ventilation / perfusion)?

Answer 4

0.8

Question 5

How does the V/Q RATIO increase within the lung?

Answer 5

Increases base to apex (more mismatch at apex)

Question 6

Would conducting bronchioles have a high or low V/Q ratio?

Answer 6

Low V/Q (very little ventilation compared to a lot of blood flow)