hema two

Question 1

41. It measures the time required to generate thrombin and fibrin polymers via intrinsic pathway.

Answer 1

aTTP

Question 2

42. The following are negatively charge particulate activator used in aPTT reagent except?

Answer 2

Thrombin

Question 3

43. An increase in aPTT will affect the following coagulation factor except?

Answer 3

Factor VII

Question 4

44. The rate of Thrombin-Induced cleavage of fibrinogen to fibrin monomers and the subsequent polymerization of hydrogen bonded polymers?

Answer 4

Thrombin time

Question 5

45. It is also known as Plasma Thromboplastin Component or Christmas factor?

Answer 5

Factor IX

Question 6

46. The following coagulation factor are consumed during the process of coagulation except.

Answer 6

Factor XII

Question 7

47. Which of the following coagulation factor is inhibited by warfarin?

Answer 7

Factor IX

Question 8

48. The specimen of the patient with prolonged aPTT was subjected to mixing studies. After an immediate mixing, it normalizes and after 2 hour incubation period, still prolonged.

Answer 8

Factor VIII inhibitor

Question 9

49. This procedure is to monitor oral anticoagulant therapy, a screening test for diagnosis of coagulation deficiencies and a component of liver profile assessment

Answer 9

Prothrombin Time or PT

Question 10

50. It involves the principle of adding of plasma to an excess extrinsic thromboplastin calcium substrate.

Answer 10

Prothrombin Time or PT

Question 11

51. The following coagulation factor therefore being detected by this test except?

Answer 11

Factor IX

Question 12

52. Which of the following coagulation factor is not consumed during a process of coagulation?

Answer 12

Factor XI

Question 13

53. Which of the following coagulation factors will be most likely affected if the patient has Vitamin K deficiency?

Answer 13

Factor IX

Question 14

54. Anti-factor aPTT is usually associated with obviously with FVIII inhibitor that is the patient is usually associated with

Answer 14

Bleeding

Question 15

55. This test is used to identify and quantitate deficiencies in the intrinsic clotting system and to control anticoagulant therapy.

Answer 15

aPTT

Question 16

56. The following coagulation factor are consumed during the process of coagulation EXCEPT

Answer 16

Proconvertin or FVII

Question 17

57. The following are the Calcium and Vitamin K independent coagulation factors except.

Answer 17

PTC or Plasma Thromboplastic Component or FIX

Question 18

58. The following are considered as serine proteases except

Answer 18

Labile or Factor V

Question 19

59. Which of the following will serve as an activator in Prothrombin Time Test?

Answer 19

Neither

Question 20

60. The following are calcium and vitamin K dependent coagulation factor except

Answer 20

Plasma Thromboplastin Antecedent of FIX

Question 21

61. The component of aPTT reagent which will activate the contact factor in intrinsic pathway

Answer 21

PF3

Question 22

62. Which of the following serves as a source of tissue factors

Answer 22

Both

Question 23

63. The primary in vivo initiation mechanism for extrinsic coagulation cascade depends on the formation of

Answer 23

Complex of Tissue factor and FVII

Question 24

64. When a person has Vitamin K deficiency, the following coagulation factor with most likely be affected except;

Answer 24

Factor V

Question 25

65. It is considered as the marker of thrombosis and fibrinolysis

Answer 25

D-dimer or Fragment D&D

Question 26

66. The component of aPTT reagent which is required to activate the prothrombin and the common pathway

Answer 26

Calcium chloride

Question 27

67. A subtype of vWD characterized by mutation within the A1 structural domain of vWF molecule

Answer 27

Subtype 2B vWD

Question 28

68. A subtype of vWD characterized by autosomal point mutation in the A2 and D1 structural domain of vWF molecule

Answer 28

Subtype 2A vWD

Question 29

69. A subtype of vWD characterized by an autosomal vWF gene missense mutation in the D9 structural domain of of vWF molecule

Answer 29

Subtype 2N vWD or Normandy Variant

Question 30

70. A subtype of vWD characterized by qualitative vWF variant that possesses poor platelet receptor binding site generating a normal multimeric distribution pattern in electrophoresis

Answer 30

Subtype 2M vWD

Question 31

71. aPTT – PROLONGED PT- PROLONGED SOLUTION: PROBLEM: X,V,II,I Aged Serum (NC) – I, II, V, VIII, XIII Aged Plasma (NC) – V, VIII Adsorbed Plasma (C) – I,V, VIII, XI, XII, XIII

Answer 31

PROACCELLERIN (Letter E)

Question 32

72. aPTT – PROLONGED PT- PROLONGED SOLUTION: PROBLEM: X,V,II,I Adsorbed Plasma (NC) – II,VII,IX,X Fresh Serum (C) – II, VII, IX, X, XI, XII Aged Serum (C) – VII, IX, X, XI, XII

Answer 32

STUART FACTOR

Question 33

73. aPTT – PROLONGED PT- PROLONGED SOLUTION: PROBLEM: X,V,II,I Fresh Serum (NC) – I, V,VIII, XIII Aged Serum (NC) – I,II, V, VIII, XIII Aged Plasma (C) – I, II, VII, IX, X, XI, XII

Answer 33

FIBRINOGEN

Question 34

74. aPTT – PROLONGED PT- PROLONGED SOLUTION: PROBLEM: X,V,II,I Adsorbed Plasma (NC) – II,VII,IX,X Fresh Plasma (C) –I, II, V, X Aged Plasma (C) – I, II, VII, IX, X, XI, XII

Answer 34

PROTHROMBIN

Question 35

75. aPTT – PROLONGED PT- PROLONGED SOLUTION: PROBLEM: X,V,II,I Fresh Serum (C) – II, VII, IX, X, XI, XII Aged Serum (C) – VII, IX, X, XI, XII Aged Plasma (NC) – V, VIII

Answer 35

NO ANSWER (Letter E)

Question 36

76. aPTT – PROLONGED PT- NORMAL SOLUTION: PROBLEM: VIII, IX, XI, XII Aged Plasma (C) – I, II, VII, IX, X, XI, XII Adsorbed Plasma (C) – I,V, VIII, XI, XII, XIII Aged Serum (C) – VII, IX, X, XI, XII

Answer 36

PLASMA THROMBOPLASTIN ANTECEDENT or HAGEMAN FACTOR (Letter E, kasi dalwa sagot!!)

Question 37

77. aPTT – PROLONGED PT- NORMAL SOLUTION: PROBLEM: VIII, IX, XI, XII Fresh Serum (NC) – I, V,VIII, XIII Aged Plasma (NC) – V, VIII Adsorbed Plasma (C) – I,V, VIII, XI, XII, XIII

Answer 37

ANTIHEMOPHLIC FACTOR A

Question 38

78. aPTT – PROLONGED PT- NORMAL SOLUTION: PROBLEM: VIII, IX, XI, XII Adsorbed Plasma (NC) – II,VII,IX,X Fresh Serum (C) – II, VII, IX, X, XI, XII Aged Serum (C) – VII, IX, X, XI, XII

Answer 38

PLASMA THROMBOPLASTIN COMPONENT

Question 39

79. aPTT – PROLONGED PT- NORMAL SOLUTION: PROBLEM: VIII, IX, XI, XII Aged Serum (NC) – I, II, V, VIII, XIII Fresh Plasma (C) –VIII, IX, XI, XIII Adsorbed Plasma (C) – I,V, VIII, XI, XII, XIII

Answer 39

ANTIHEMOPHLIC FACTOR A

Question 40

80. aPTT – PROLONGED PT- NORMAL SOLUTION: PROBLEM: VIII, IX, XI, XII Adsorbed Plasma (NC) – II,VII,IX,X Aged Serum (C) – VII, IX, X, XI, XII Aged Plasma (C) – I, II, VII, IX, X, XI, XII

Answer 40

CHRISTMAS FACTOR