IBD Flashcards

(46 cards)

1
Q

Aminosalicytes

A
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2
Q

what are the drugs that are turning into Mesalamine to be active?

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3
Q

various products release differently in the multiple GI tract areas depending on the formulation, allowing for targeted drug therapy

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4
Q

Budesonide

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5
Q

Predisone

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6
Q

Immunomodulators - Thiopurines

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7
Q

Immunomodulators:
Methotrexate (Rheumatrex)

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8
Q

Anti-TNF monoclonal antibodies

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9
Q

Anti-TNF monoclonal antibodies (repeated doses)

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10
Q

Anti-IL-12/IL-23:
Ustekinumab

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11
Q

Anti-Integrins:
Vedolizumab

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12
Q

induction of remission in mild UC: mild proctits, mild left sided colitis, mild extensive colitis

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13
Q

Cyclosporine

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14
Q

lifestyle modifications evidecne in GERD

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15
Q

JAK inhibitors

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16
Q

vaccination

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17
Q

GERD (infrequent heartburn) and (troublesome sx &/or GERD complications) tx

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18
Q

Antiacids

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19
Q

Histamine-2 receptor antagonists use and MOA

20
Q

Histamine-2 receptor antagonists AE and DI

22
Q

Omeprazole and Dexlansoprazole

23
Q

PPI short term vs log term use

24
Q

Duration of PPI therapy

25
what is the controversy with PPI?
26
drug therapy for PUD
27
optimized bismuth BQT
28
plyera
29
Rifabutin triple therapy
30
Rifabutin triple therapy AE, CI, DI
31
Vonoprazan
32
PCAB treatment of H.pylori
33
Post Eradication of H. Pylori: - duodenal - small gastric ulcers - large gastric ulcers or complicated
33
1st line regimens for treatment naive patinets with H. pylori infection (PNC allergy vs no PCN allergy)
33
what should be avoided unless there is demonstrated sensativity to Macrolides & Quinolones
34
NSAID-induced ulcers: -inhibition of COX 1 - nonselective NSAIDs carry
35
MOA of NSAIDs
36
what are the risk factors for NSAID PUD: low medium high
37
what are the recommendations for prevention of NSAID- iduced ulcers?
38
risk reduction from NSAIDs: - patients with 1-2 GI risk factors - mutiple GI risks factors - all pts who take NSAIDs plus low-dose aspirin or clopidogrel (or both) should also take a PPI daily
39
Treatment of NSAID-induced ulcers: - PPI if <1cm - PPI if >1cm
40
prevention of recurrent ulcers
41
sucralfate (carafate)
42
Misoprostol (Cytotec)
43
treatment of ulcers NOT attributeable to H pylori or NSAIDs
44
monitoring patinet response