IBS

Question 1

female to male ratio

Answer 1

2:1

Question 2

ROME III criteria

Answer 2

recurrent abdominal pain for 3days a month for 3 months and at least 2 of:

• improvement with defecation
• change in stool appearance
• change in stool frequency

Question 3

aetiology

Answer 3

unknown but thought to be attributed to visceral hypersensitivity

Question 4

ALARM symptoms that suggest deeper cause

Answer 4

age > 50 
more recent onset 
wake up from sleep for toilet 
rectal bleeding 
weight loss and anaemia 
family history of colorectal cancer

Question 5

symptoms

Answer 5

bloating 
abdominal discomfort 
inc frequency of toilet visits 
mucus stool 
incomplete emptying

Question 6

non GI symptoms

Answer 6

TMJ dysfunction
chronic pelvic pain
fibromyalgia
chronic fatigue or depression

Question 7

investigations

Answer 7

normal but abdominal tenderness

FBC
CRP
antibody for coeliac

Question 8

O/E

Answer 8

normal but abdominal tenderness

Question 9

treatment pharmacological

Answer 9

anti -
spasmodic
depressant
diarrhoeal

Question 10

name an anti spasmodic

Answer 10

mebeverine hyoscine

Question 11

name an antidiarrhoeal

Answer 11

loperamide

Question 12

what drugs are contraindicated

Answer 12

anti motility (diarrhoea) e.g. opiates