IHD

Question 1

ATP depletion in IHD

Answer 1

onset of ATP depletion in seconds

reduced to 50% in 10 minutes

reduced to 10% in 40 minutes

Question 2

timing of loss of contractility in IHD

Answer 2

< 2minutes

Question 3

Irreversible cell injury timing in IHD

Answer 3

20-40 mins

Question 4

Microvascular injury timing in IHD

Answer 4

> 1 hour

Question 5

What is the most common histological change seen within 24 hours following a myocardial infarction?

Answer 5

Coagulative necrosis
Pallor
Oedema
Haemorrhage
Pyknosis of nuclei

Question 6

What is the most common histological change seen within 3-7 days following a myocardial infarction?

Answer 6

disintegration of myofibres

Question 7

What is the most common histological change seen at 2 to 8 weeks following a myocardial infarction?

Answer 7

Collagen deposit

Question 8

How long does it take troponis levels to return to normal after an AMI?

A 5-7 days
B 3-5 days
C 72hrs
D 48hrs

Answer 8

A 5-7 days

Serum levels increase within 3-12 hours from the onset of chest pain, peak at 24-48 hours, and return to baseline over 5-14 days