Colchicine and Statins
Best to avoid because it can increase the risk of rhabdomyolysis eg breakdown of muscle tissue = pain
Probenecid and methotrexate
Be mindfull that Probenecid can keep methotrexate in he body for longer thus increases toxicity risk
Allopurinol and what other immunosuppressant?
Azathioprine and mercaptopurine
-these drugs are generally used in organ transplant - thus any concentration decrease may cause the organ to be REJECTED - very bad news