KIDD

Question 1

INTRO:
1. ____ & colleagues reported finding Ab in serum of Mrs. Kidd, whose infant had HDFN

Answer 1

ALLEN

Question 2

KIDD ANTIGENS

1. Jka & Jkb are commonly found on
2. Jk is detected as early as
3. Jkb is detected at

Answer 2

1. RBCs
2. 11 weeks
3. 7 weeks

Question 3

KIDS ANTIBODIES

______: Kidd antibodies have a notorious reputation in the blood bank

1. dosage are often _______
2. agglutination best observed by
3. antibody reactivity can also be enhanced by using _____ or ____ (to promote IgG attachment),
   - or using _____ instead of 2 (to increase antibody-to-antigen ratio)
   - or by using enzymes such as ____ or ____
4. _____ store well

______: associated w/ severe immediate & delayed HTRs and w/ mild HDFN
1. manifested w/ _____ phenotype
- who inherited the ______

Answer 3

anti-Jka & antics Jkb

1. WEAK
2. IAT
3. LISS/ OEG
   - 2 drop of serum
   - FICIN or papain
4. D NOT store well

anti-Jk3
1. Jk(a-b-)
- silent gene JkJk

Question 4

Phenotypes of Kidd

Jk(a-b-) have 2 causes

1. common allele in Polynesians, Filipinos, Indonesians, & Chinese
   - delayed lysis in ________
   - taking up ___mins
2. inheritance within Japanese family

Answer 4

1. Jk(a-b-) phenotype & recessive allele, Jk
   - 2M urea
   - 30mins
2. Jk(a-b-) phenotype & dominant In(Jk) allele