L1 Brain Development

Question 1

1. Which statements on neuronal development are correct:
2. following vertical cleavage at the ventricular surface, both daughter neuroblasts can divide again
3. lower motor neurons develop from neural crest cells
4. precursors neurons exposed to bone morphogenic proteins (BMPs) become sensory neurons

• 1, 2
• 2, 3
• 1, 3
• all are correct

Answer 1

Correct: 1, 3

That is:

• 1. is correct: vertical cleavage happens at the ventricular surface, and both daughter neuroblasts can divide again
• 2. is incorrect: lower motor neurons develop from the basal plate cells of the neural tube. Neural crest cells go on to form the peripheral and autonomic nervous systems.
• 3. is correct: neuroblasts exposed to BMPs on the alar plate become sensory neurons