lecture 14

Question 1

what is the definition of a MI/AMI

Answer 1

interruption of blood supply to part of the heart, caisong some heart cells to die.

Question 2

What comorbidity do most patients who sustain a MI have

Answer 2

coronary atherosclerosis

Question 3

what happens in the progression to a heart attack

Answer 3

thrombus formation occurs - usually at the site of an atherosclerotic lesion which obstruts blood flow to the myocardial tissues.

Question 4

what is belived to be the trigger mechanism for thrombus formation in MI patients

Answer 4

plaque rupture

Question 5

what is an NSTEMI and how does it occur

Answer 5

non st elevation MI - caused by a complete occlusion of minor coronary artery or a partial occlusion of a major coronary artery. This causes partial thickness damage of heart muscle

Question 6

whats a STEMI and how does this occur

Answer 6

st elevation MI - caused by complete occlusion of a major coronary artery previously affected by atherosclerosis - causes full thickness damage of heart muscle.

Question 7

how does the time between occlusion and perfusion relate to damage

Answer 7

shorter time between occlusion and perfusion , the less damage and greater myocardial tissue that can be salvaged