what leads to genetic uniformity of breeds
deliberate inbreeding(homozygosity)
linebreeding definition
mating of animals within a particular line
what is the purpose of linebreeding
-fixing desirable genotypes
-purging deleterious recessive alleles
structured inbreeding systems
linebreeding
full-sib mating
self fertilization
breeding to same ancestor
what example from class showed a closed line? how long had it been closed?
USDA-ARS miles city hereford bulls
closed since late 1930s
example of prominent bulls used for inbreeding
Advanced Domino-1931
Prince Domino-1914
Bufford of Wye
Manso
example of prominent horses used for inbreeding
Old Sorrel-1914
Jack McCue- quarter horses
what ranch was old sorrel on
king ranch
what is the length of an ROH an indication of
consanguinity(genetic relation)
-long=recent inbreeding
-short=far out inbreeding
how can regression information be used
-identify animals that are ‘less inbred’ than predicted by pedigree averages
-design heterozygosity
-controlled inbreeding
what is regression/ROH
identifies places where animals are homozygous for all or most of the SNPs
