METHOXYFLURANE

Question 0

PHARMACOLOGY OF METHOXYFLURANE

Answer 0

Inhalation analgesic agent at low concentrations

Question 1

PRESENTATION OF METHOXYFLURANE

Answer 1

3 mL glass bottle

Question 2

PRIMARY EMERGENCY INDICATIONS FOR METHOXYFLURANE

Answer 2

Pain relief

Question 3

CONTRAINDICATIONS OF METHOXYFLURANE

Answer 3

1. Pre-existing renal disease/ renal impairment
2. Concurrent use of tetracylcine antibiotics
3. Exceeding total dose of 6mL in a 24 hr period

Question 4

PRECAUTIONS FOR METHOXYFLURANE

List all 3

Answer 4

1. The Penthrox inhaler must be hand - held by the Pt so that if unconsciousness occurs it will fall from the Pts face. Occasionally the operator may need to assist but must continuously assess the level of consciousness
2. Pre-eclampsia
3. Concurrent use with Oxytocin may cause hypotension

Question 5

ROUTE OF ADMINISTRATION FOR METHOXTFLURANE

Answer 5

Self-administration under supervision using the hand held Penthrax inhaler with or without O2 supplementation

Question 6

SIDE EFFECTS OF METHOXYFLURANE

Answer 6

Drowsiness
Decrease in blood pressure and bradycardia (rare)
Exceeding the maximum total dose of 6mL in a 24 hr period may lead to renal toxicity

Question 7

SPECIAL NOTES FOR METHOXYFLURANE

Answer 7

• Initial priming dose is 3mL
• Will provide approximately 25min of analgesia and may be followed by one further 3mL dose, once the initial dose is exhausted if required.
• Analgesia commences after 8-10 breaths and lasts for approximately 3 - 5 min once discontinued.
• Do not administer in a confined space. Ensure adequate ventilation in amublance