what are the active proteins within skeletal muscle
- actin
- myosin
what are the regulatory proteins in skeletal muscle
- tropomyosin
- troponin
- myosin light chain
what are the structural proteins of skeletal muscle
- nebulin
- titin
- desmin
- skelemin
- dystrophin
- integrins
what is the function of tropomyosin
regulates interaction between actin and myosin, stabilizes actin filament
troponin function
influences position of tropomyosin binds with Ca2+
myosin light chain function
influences contraction velocity of the sarcomere, modulates kinetics of crossbridge cycling
nebulin function
anchors actin to Z discs
function of titin
acts as spring to confer elasticity to sarcomere, and help recoil after being stretched
desmin function
helps stabilize longitudinal and lateral alignment of adjacent sarcomeres
function of vimentin
helps maintain periodicity of Z discs
skelemin function
helps stabilize the position of M lines
dystrophin function
provides structural stability to the cytoskeleton and sarcolemma of muscle fiber
function of integrins
stabilize cytoskeleton of muscle fiber
muscle spindle (primary) function
stimulus is rate of muscle stretch, increases excitability of agonist muscle, decreases excitability of antagonist muscle
golgi tendon organ function
decreases excitability of agonist muscle, increases excitability of antagonist muscle, stimulus is muscle-tendon force
muscle spindle (secondary) function
increases excitability of agonist muscle and stimulus is muscle stretch
function of mechanoreceptor
increases cardiovascular and ventilatory output, inhibits central motor drive, stimulus is change of intramuscular pressure
metaboreceptor function
function is similar to mechanoreceptors and stimulus is also change of muscular metabolism
