Motion Sickness

Question 1

uncomfortable, queasy feeling that one may vomit

Answer 1

nausea

Question 2

chemoreceptor trigger zone contains receptors for

Answer 2

DA
5-HT
ACh

Question 3

dizziness with the sensation the environment is moving or spinning, typically due to an inner ear condition

Answer 3

vertigo

Question 4

dizziness with a sensation of being off balance and woozy due to repetitive motions

Answer 4

motion sickness

Question 5

general treatment for nausea

Answer 5

5HT3 RAs- ondansetron
DA block- propchlorperazine
5HT and DA block with metoclopramide

Question 6

general treatment of vertigo

Answer 6

antihistamines and BZDs (inner ear suppressants)

Question 7

general treatment of motion sickness

Answer 7

anticholinergics, antihistamines

Question 8

natural option for nausea

Answer 8

ginger

Question 9

anticholinergic option with less frequent dosing (3 days) and can be placed behind the ear

Answer 9

scopolamine

Question 10

antihistamines used for motion sickness

Answer 10

diphenhydramine, dimenhydrinate, meclizine

Question 11

oral antihistamines but be taken ___ prior to needed effect

Answer 11

30-60 minutes

Question 12

medications for motion sickness cause

Answer 12

drowsiness

Question 13

all antihistamines have __ effects

Answer 13

anticholinergic

Question 14

RX only option for motional sickness, but should not be used in children

Answer 14

promethazine

Question 15

nausea options that are NOT recommended for motion sickness

Answer 15

metoclopramide, 5HT3 RAs

Question 16

brand name scopolamine

Answer 16

Transderm Scop

Question 17

how to use scopolamine for motion sickness or surgery

Answer 17

1 patch behind the year Q3D PRN

apply 4 hours before needed or night before surgery
press firmly for 30 seconds
avoid placing over hair (patch may remove it)
last 3 days, replace if still needed behind other ear
wash hands after applying

Question 18

contraindications to scopolamine

Answer 18

hypersensitivity to belladonna, closed-angle glaucoma

Question 19

AEs of scopolamine

Answer 19

dry mouth
CNS- drowsy, dizzy, confusion
stinging of eyes, pupil dilation, inc IOP, withdrawal symptoms after d/c

Question 20

remove scopolamine patch before

Answer 20

MRI

Question 21

avoid ___ while wearing scopolamine patch

Answer 21

alcohol

Question 22

brand name dimenhydrinate

Answer 22

Dramamine

Question 23

warnings for dimenhydrinate and meclizine

Answer 23

CNS depression, inc IOP (glaucoma)

Question 24

AEs of dimenhydrinate and meclizine

Answer 24

dizziness, drowsiness, dry mouth, blurry vision

Question 25

brand name of meclizine

Answer 25

Dramamine less drowsy

Question 26

meclizine is commonly used for

Answer 26

vertigo

Question 27

do not ___ while using scopolamine - high level of drowsiness, dizziness, and confusion which is worse in elderly

Answer 27

drive