Narcan

Question 1

Narcan - Generic Name

Answer 1

Generic: Naloxone

Question 2

Narcan - MOA

Answer 2

MOA
Competitive narcotic antagonist

Competes for narcotic receptors in brain – displace narcotic molecules from receptors

Treat narcotics and synthetic narcotic agents

Question 3

Narcan - Class

Answer 3

Class: opioid antagonist

Question 4

Narcan - Indications

Answer 4

Indications
Complete or partial reversal of CNS and respiratory depression from opioids

Heroin, meth, Demerol. Codeine, morphine, talwin, darvon, Percodan, Percocet, fent

Question 5

Narcan - Contraindications

Answer 5

Contraindication
Hypersensitivity

Question 6

Narcan - Precautions

Answer 6

Precautions
Use with caution – pt go into withdrawal

Question 7

Narcan - Interactions

Answer 7

Interactions
None in emerg setting

Question 8

Narcan - Side Effects

Answer 8

Side effects
Narcotic withdrawal syndrome
Nausea/vomit
Cardiac dysrhythmias
Hypotension
Hypertension

Question 9

Narcan - Dose

Answer 9

Dosage – titrate to effect
Adult: 0.4 mg IV/IO/IM total max of 2 mg
1.0 mg per nare intranasal (IN) (repeat q 3-5 minutes prn)

Peds: 0.1 mg/kg IV/IO/IM to max of 2 mg

Question 10

Narcan - Action Times

Answer 10

Action times
Onset <2 minutes IV/IO, 2-10 minutes IM/ETT
Peak effects w/in < 2 minutes IV/IO, 2-10 minutes IM/ETT
Duration: 20-120 minutes
½ life: 60-90

Question 11

Narcan - Preparation

Answer 11

Preparation
2mg in 2mL vials