What’s the medication indicated for non-metastatic castrate resistant prostate cancer
Androgen receptor blocker
What’s bone-seeking isotope?
It’s a treatment for metastatic prostate cancer
What treatment does a patient with small cell lung cancer with complete response after Qt and Rt?
Prophylactic cranial irradiation
Whats the treatment for non–small cell lung cancer who are not candidates for surgery?
For patients with non–small cell lung cancer who are not candidates for surgery, stereotactic radiation therapy can be used to treat stage I cancers.
What’s the indication of HT screening of pts on trastuzumab?
TTE for those at high risk
2 of: DM, HTN, DLP, smoking, obesity
> 60 yo on dx
concurrent use of anthracicline
Treatment of cancer of unknown primary
If advanced, should start chemo: unless finding the primary source would change management
Metastatic cancer of unknown primary in women and abd carcinimatosis: how to approach
Women who have adenocarcinoma with abdominal carcinomatosis and ascites should be presumptively treated for ovarian cancer.
Patients with bulky or locally advanced stage III cervical cancer
Cisplatin and radiation therapy
Pt with previous breast cancer history and new axillary lymph node + new pulmonary nodules: what to do
Biopsy the PULMONARY nodule: bx whatever upstages the pt
Women with advanced ovarian cancer and BRCA mutations who achieve some response to platinum-based chemotherapy should receive
maintenance therapy with a poly (ADP-ribose) polymerase inhibitor.
Patients who have good performance with metastatic non–small cell lung cancer with negative PD-L1 treatment
Pembrolizumab + chemotherapy (regardless of PD-1 status)
Treatment of depression in patients taking tamoxifen
Antidepressants with strong CYP2D6 inhibition, such as bupropion or fluoxetine, may decrease tamoxifen activation and should be avoided. Use venlafaxine
Well-differentiated, low-grade, metastatic gastrointestinal neuroendocrine tumors, treatment?
indolent and asymptomatic and do not require immediate treatment: expectant observation
Genetic testing for BRCA gene mutation should be done in all men with prostate cancer and…
high-risk disease, including patients with a Gleason score >7, positive lymph nodes, or metastatic disease
For women survivors of Hodgkin lymphoma who received chest irradiation between ages 10 and 30 years, breast CA screening?
Annual breast cancer screening with MRI is recommended to begin 8 to 10 years post-therapy or at age 25 years, whichever comes last, with mammography in addition to MRI beginning at age 30 years
Treatment of extra-gastric MALT
The treatment of mucosa-associated lymphoma tissue (MALT) lymphomas other than gastric MALT lymphoma may include irradiation for localized disease or rituximab when systemic therapy is required.
For patients who have breast cancer with bone metastases, additional treatment other than chemo
bone-modifying agents such as zoledronic acid or denosumab are recommended to prevent bone-related events
Texturized breast implant with periprosthetic fluid collection
Anaplastic large cell lymphoma
In men undergoing active surveillance for prostate cancer, what change in PSA warrants re-biopsy?
Doubling in less than 3 years
Indication of androgen receptor blocker in patients with prostate cancer
castrate-resistant prostate cancer with rapidly rising prostate-specific antigen levels
For patients with hormone receptor–positive, human epidermal growth factor 2–negative breast cancers with no positive axillary nodes, treatment?
Determined by multigene assays
For metastatic non–small cell lung cancer with an ALK translocation, treatment?
Alectinib
What to test with the gastroesophageal tumors that determines therapy?
Testing HER2 (human epidermal growth factor receptor) overexpression: to add trastuzumab
