Ondansetron Class
Anti-emetic, Selective seratonin receptor antagonist
Ondansetron MOA
Selective 5HT-3 seratonin antagonist in the CNS at the chemoreceptor trigger zone and in the PNS on the nerve terminals of the vagus nerve, blocking nausea and emesis
Ondansetron Indication
Nausea and or vomiting
Ondansetron Contraindication
Congenital long QT syndrome
Ondansetron Adult Dose
4mg IVP/ODT + 2 repeats
Ondansetron Pregnancy Class
B (not harmful to animals, untested in humans) caution should be used in first trimester
Ondansetron Broselow White and Smaller IV/IM Dose
BHO 0.1mg/kg max 4mg IV/IM
Ondansetron Broselow Red and Smaller ODT Dose
BHO 4mg ODT