Pasteurella multocida

Question 1

Physical description of pasteurella

Answer 1

• G negative
• coccobacilli
• facultative anaerobe
• 4 capsular antigens types

Question 2

Clinical presentation of pasteurella

Answer 2

• local or disseminated edematous soft tissue abscess
• rapidly progressive cellulitis
• following animal bite
• fowl; pneumonia
• cattle; fever
• rabbits; snuffles to hemorrhagic pneumonia

Question 3

Epidemiology of pasteurella

Answer 3

• almost always spread to humans by animal bites

- spread by fomites

Question 4

Pathogenesis of pasteurella

Answer 4

• antiphagocytic capsule
• pili, adhesion proteins, Fe binding proteins
• adheres to M phages but not engulfed
• growth in vivo as fast as in vitro
• growth and abscess formation is pathogenesis

Question 5

Control of pasteurella

Answer 5

• pen/amp. or ceph + tetracycline

- most animal bite infections are polymicrobial