Pharm

Question 1

First order kinetics

Answer 1

Constant percentage
20->10->5->2.5
Kel Constant
Half life independent of dose

Question 1

Zero order kinetics

Answer 1

constant amount of drug removed from body
Kel variable
20->15->10
Half life depends on dose

Question 2

Volume of distribution (L/kg)

Answer 2

Total amount of drug (mg/kg)/ plasma conentration (mg/L)

Question 3

Half life

Answer 3

0.693/Kel

Question 4

Kel

Answer 4

Cl/Vd or ln(Cmx-Cmin)/t

Question 5

Clearance (L/hr*kg)

Answer 5

(dose/interval)/avg steady-state [drug]