Likelihood ratio for positive result
sensitivity/(1-specificity)
Likelihood ratio for negative result
Specificty/(1-senstivity)
Confidence interval
Point estimate +/- (1.96 x SD/sqrt n)
Kruskal Wallis
Comparing more than two medians (ordinal variables)
Mann-Whitney U
comparing two medians
Neonatal mortality
Death <28 days
(infant mortality is death <1yo)
Perinatal mortality
Fetal death >28 weeks + death up to 7 days
Clinical Trials
Phase 1: Establishing a safe range for dosing and documenting side effects
Phase 2: Assessing effectiveness of therapy and further assess safety
Phase 3: Comparing effectiveness against another therapy
Phase 4: tracking safety in general public,