What is the difference between mediation and moderation?
Mediation
- answer questions about why/how
- ex-> why do people experience less depression when undergoing behavioural activation
- about mechanisms of intervention
- third variable
Moderation
- answer questions about for whom and to what extend
- ex-> who benefits the most from behaivoural activation in term of depressive symptoms?
- individuals differences in response to intervention
- degree or size
Why can focusing on reduction of psychological symptoms be problematic?
Usually treatment development focus on reduction of psychological symptoms which can be problematic because
- based on DSM which is criticize
- excessive co-occurence
- many risk and maintenance mechanisms are common to multiple psychological disorders→ avoidance, emotion regulation…
What is process-based therapy?
Not outcome based therapy→ do not look at what therapy works better on average
- BUT look at process based therapy
- how does change comme about
- look at treatment explaining individuals differences
- what changes procedures are most effective
- what specific treatment works best
use the diemnsional model extended evolutionary meta-model (EEMM)
How can research identify a mediator?
For mediation
- need to establish that mechanism is malleable
- mechanism relates strongly to both intervention and outcome
- Effect is specific and replicable across studies
- temporal precedence→ timeline is established, such that change in mechanism precedes change in outcome
—>BUT, statistically significant mediation does not = a mechanism
How can research identify a moderator?
For moderation→
- Most often, demographic and other “moderators of convenience” are tested
- Can identify moderators based on knowledge of mechanisms, and moderator studies can further inform us about mechanism
—>moves from nomothetic to idiographic research methods
How can research identify mediators and moderators?
How to do that
- functional analysis to look at maintaining contingencies
- used EMA to gather info for real life
What is a difference between a change processe and a change procedure?
Change processes VS change procedure
- Cognitive defusion VS mindfulness
- Avoidance VS exposure
- Emotion regulation VS cognitive reappraisal
How is process-based therapy usually structured?
What is personalizing psychotherapy?
Stumpp and Sauer-Zavala, 2021
- use patient’s preferences
- evidence based decisions for which part of treatment to focus on
Which characteristics of the individual can we personalize psychotherapy for?
Personalize psychotherapy for
- Diagnosis
- Specific symptoms/psychological processes
- Personality traits
- Pre-existing psychological skills (capitalization→ enhancing strength vs. compensation→ targeting weaknesses)
- Response to treatment (and reasons for lack of response)
- Change in psychological mechanisms over time
Which aspects of treatment can we personalize psychotherapy for?
Treatment selection
Inclusion of therapy skills
Order of therapy skills
- compensation, capitalization
Treatment changes
- Routine outcome monitoring
- SMARTs
Session frequency
Treatment termination
- brief VS full treatment
What is some research evidence for personalizing psychotherapy?
Research evidence→ Sauer-Zavala, 2022
- SMART design to test personalization of unified protocol→
- examine effects of order of modules on rate of symptom improvement
- compared personalized selection of modules to full treatment
- 70 patients with emotional disorder
- randomized groups of standard, capitalization or compensation conditions
- after 6th session→ randomized to discontinue or full treatment
Results
- people liked the standard and capitalization a bit better than compensation
- prefer full treatment compared to discontinued treatment
- BUT no differences in symptoms reduction between the conditions
What are the different modules of the unified protocol for emotional disorders?
Transdiagnostic treatment for people with emotional disorders
- could also be for ED, SUD or BPD
Modules
- Understanding emotions
- Increasing present-focused emotional awareness
- Increasing cognitive flexibility
- Identifying and preventing patterns of emotional avoidance and maladaptive emotion-driven behaviours
- Increasing awareness and tolerance of emotion-related physical sensations
- Interoceptive and situation-based emotion-focused exposure
What is some research evidence for the unified protocol for emotional disorders?
Research evidence→ Farchione et al., 2012
- UP vs. wait-list control for patients with a principal anxiety disorder
- UP improved symptoms of anxiety and depression, levels of negative and
positive affect, and symptom interference in daily functioning
- Effects maintained over 6-month follow-up
Limitations
- No comparison to diagnosis-specific treatments
- Limited longitudinal follow-up data
- Limited data in other populations with problems with emotion regulation
Explain the case of Amy using process-based therapy
Ong et al, 2023→ case of Emmy with GAD
- need to check things, indecision
- clarify values, more active,
- the distinct feature of PBT is that it also identifies the downstream and upstream variables tied to worry
- use a network modeling
- black arrow→ positive relation
- white arrow→ inhibitory effects
- create a self-amplifying loop
—>all of this maintain her GAD
- came from a personalized ecological momentary assessment
- use it to always update the network