define motor unit
motor neuron and all fibers it innervates
define motor neuron pool
all axons that innervate a muscle
what are lower motor neurons, and what do they include?
motor neurons of the brainstem & spinal cord that innervate skeletal muscle:
- ventral horn cells & processes
- motor nuclei of CNs & processes
name the 2 types of ventral horn cells
alpha motor neurons
gamma motor neurons
what do alpha (a) motor neurons innervate?
extrafusal skeletal muscle fibers
what do gamma (y) motor neurons innervate?
intrafusal fibers (specialized skeletal muscle fibers enclosed in a fibrous capsule called a muscle spindle)
symptoms of LMN lesion
what are fasciculations?
visible muscle twitching resulting from involuntary synchronous contraction of all muscle fibers in a motor unit
fasciculations are characteristic of…
slowly progressive diseases of the motor unit
what are fibrillations?
spontaneous activity of one muscle fiber detected only with electromyography
fibrillations are a sign of…
progressed muscle denervation or myopathy
what is a muscle spindle?
what is the motor innervation of muscle spindles?
gamma (y) motor neurons
describe alpha and gamma co-activation
why is alpha and gamma co-activation important?
ensures extrafusal and intrafusal fibers are in sync
what is the sensory innervation of muscle spindles?
Ia (annulospiral endings) fibers and II (flower spray) fibers that detect muscle stretch
name the 3 types of intrafusal fibers
what are nuclear chain fibers?
what are nuclear bag fibers?
thicker intrafusal fibers, with nuclei grouped in the central region
what are dynamic nuclear bag fibers?
what are static nuclear bag fibers?
what is the stretch (deep tendon) reflex?
monosynaptic (no interneuron) connection between central axon of Ia fiber and the a-motor neuron, causing muscle contraction in response to stretch
in the stretch reflex, the ____ muscle is excited via the ____ neuron
agonist
alpha motor
what is the sensory receptor of the stretch reflex?
muscle spindle