reproduction Flashcards

(59 cards)

1
Q

Why is the reproductive system not essential for individual survival

A

Because its primary role is ensuring species survival, not maintaining homeostasis in the individual

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2
Q

What are the main components of the reproductive system?

A

. Gonads (testes/ovaries), reproductive tracts (specialized ducts), accessory sex glands, and external genitalia

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3
Q

What are secondary sexual characteristics, and which hormones control them?

A

Traits distinguishing males from females (e.g., hips, beards, hair patterns). Estrogen drives female traits, testosterone drives male traits. Progesterone is not involved.

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4
Q

What is the role of meiosis in gametogenesis?

A

It reduces chromosome number by half, producing haploid gametes and ensuring genetic variation

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5
Q

Compare spermatogenesis and oogenesis.

A
  • Spermatogenesis: Continuous from puberty, millions of sperm daily, each primary spermatocyte yields 4 viable sperm.
  • Oogenesis: Begins in fetal life, cyclic from puberty, limited oocytes, each primary oocyte yields 1 ovum + 3 polar bodies.
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6
Q

When does oogenesis begin and end?

A

Begins during fetal life (meiotic arrest), resumes at puberty, and continues cyclically until menopause

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7
Q

How is genetic sex determined at conception?

A

By the sperm’s chromosome: XX = female, XY = male.

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8
Q

What role does the SRY gene play in differentiation

A

It codes for testis-determining factor (TDF), which directs gonads to form testes.

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9
Q

What happens if androgens are absent during development?

A

Female external genitalia and reproductive tract develop by default.

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10
Q

Name two disorders of sexual differentiation and explain them

A
  • Testicular feminization syndrome: Genetic male develops female anatomy due to non-responsiveness to testosterone.
  • Androgenital syndrome: Female fetus exposed to excess androgens develops male-like features
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11
Q

What are the two main functions of the testes?

A

Produce sperm (spermatogenesis) and secrete testosterone

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12
Q

Which cells produce testosterone in the testes

A

. Leydig (interstitial) cells between seminiferous tubules.

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13
Q

What are the main functions of Sertoli cells?

A

Nourish sperm, form blood-testis barrier, phagocytose waste, secrete fluid for sperm transport, secrete androgen-binding protein, release inhibin, and regulate spermatogenesis.

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14
Q

What condition occurs if testes fail to descend into the scrotum?

A

Cryptorchidism, which prevents viable sperm production.

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15
Q

What are the parts of a sperm cell and their functions

A
  • Head: Contains DNA.
  • Acrosome: Enzyme cap for ovum penetration.
  • Midpiece: Mitochondria for energy.
  • Tail: Provides motilit
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16
Q

List the five categories of testosterone effects

A

1) Reproductive system before birth, (2) sex-specific tissues after birth, (3) other reproductive effects, (4) secondary sexual characteristics, (5) non-reproductive actions (e.g., anabolic effects).

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17
Q

What roles does testosterone play during puberty?

A

Maturation of gonads, development of secondary sexual traits, libido, reproductive tract growth, and pubertal growth spurt.

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18
Q

What does the seminal vesicle contribute to semen?

A

Fructose (energy), prostaglandins (contractions), fibrinogen (clot formation

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19
Q

What is the contribution of the prostate gland?

A

Alkaline fluid (neutralizes vaginal acidity), clotting enzymes, and fibrinolysin

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20
Q

What do the bulbourethral glands secrete

A

Lubricating mucus for penetration

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21
Q

What are the phases of the male sexual response cycle?

A

Excitement (erection), plateau (intensifying arousal), orgasmic (ejaculation), and resolution (return to baseline

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22
Q

How does the female sexual response differ from males?

A

. Females have no ejaculation and no refractory period after orgasm

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23
Q

What are the main functions of the female reproductive system

A

Oogenesis, sperm reception, gamete transport, fertilization, gestation, placental formation, parturition, and lactation.

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24
Q

What is the function of the uterus?

A

Maintains the fetus during pregnancy and delivers it at birth.

25
What is the vulva?
Collective term for external female genitalia (labia, clitoris, vaginal opening
26
What are the roles of estrogen and progesterone
* Estrogen: Ova maturation, secondary traits, sperm transport, breast development. * Progesterone: Prepares uterus for implantation and supports breast function for lactation.
27
What are the two phases of the ovarian cycle?
Follicular phase (days 1–14, follicle growth and estrogen secretion) and luteal phase (days 15–28, corpus luteum secreting progesterone
28
What is the zona pellucida?
A glycoprotein layer around the oocyte, separating it from granulosa cells and allowing molecule exchange.
29
What hormonal change triggers menstruation?
Decline in estrogen and progesterone due to degeneration of the corpus luteum
30
What triggers ovulation?
A surge in LH secretion, which resumes meiosis, ruptures the follicle, and converts it into the corpus luteum.
31
How do estrogen and progesterone regulate the pituitary?
* Moderate estrogen: Negative feedback → suppresses FSH & LH. * High estrogen: Positive feedback → LH surge. * Progesterone: Negative feedback → suppresses GnRH & LH.
32
What is the role of inhibin in reproduction?
. It selectively inhibits FSH secretion, regulating follicular recruitment.
33
Where does fertilization normally occur?
In the ampulla of the fallopian tube.
34
What is the role of the acrosome during fertilization
It releases enzymes that digest the zona pellucida, allowing sperm to penetrate the ovum
35
How is polyspermy prevented after fertilization
A cortical reaction hardens the zona pellucida after one sperm enters, blocking additional sperm.
36
What is implantation?
The embedding of the blastocyst into the endometrium, usually 6–7 days after fertilization
37
What are the main functions of the placenta?
Nutrient, gas, and waste exchange; hormone production (hCG, progesterone, estrogen, human placental lactogen
38
What is the role of hCG?
Maintains the corpus luteum during early pregnancy until the placenta takes over hormone production.
39
Which hormones prepare the breasts for lactation
Estrogen and progesterone (development), prolactin (milk production), oxytocin (milk ejection).
40
How does suckling trigger milk ejection
Nipple stimulation → hypothalamus → oxytocin release from posterior pituitary → contraction of myoepithelial cells → milk let-down
41
Why can breastfeeding suppress ovulation
Prolactin inhibits GnRH, reducing FSH and LH, which prevents ovulation in some women
42
What are the three phases of the uterine cycle?
Menstrual phase (shedding), proliferative phase (estrogen-driven repair), secretory phase (progesterone-driven preparation).
43
What causes menstrual cramps (dysmenorrhea)?
. Uterine prostaglandins cause vasoconstriction and myometrial contractions
44
Which hormone prepares the endometrium for implantation?
Progesterone.
45
What triggers puberty in females?
. Increased GnRH secretion → ↑ estrogen → maturation of reproductive system & secondary traits.
46
What are common effects of menopause?
Hot flushes, irregular cycles, vaginal dryness, osteoporosis, cardiovascular risks, and climacteric transition
47
Where does fertilisation usually occur, and within what timeframe?
In the oviduct (ampulla), within 24 hours after ovulation
48
What is the difference between morula and blastocyst?
. Morula = solid ball of cells; Blastocyst = hollow with inner cell mass (embryo) and trophoblast (placenta).
49
What is an ectopic pregnancy?
When implantation occurs outside the uterus, usually in the oviduct
50
Which contraceptive methods inhibit ovulation?
Oral contraceptives and implants
51
Which method has the lowest failure rate?
Implanted contraceptives (~1%).
52
What hormones are secreted by the placenta?
hCG, progesterone, estrogen, and human placental lactogen
53
What is the role of hCG during early pregnancy?
Maintains corpus luteum until the placenta takes over hormone production.
54
What maternal changes occur during pregnancy?
Uterine enlargement, breast growth, ↑ blood volume, ↑ respiration, ↑ kidney output, ↑ nutrition demand
55
Which hormones initiate labour?
. Estrogen (oxytocin receptors, prostaglandins), oxytocin (uterine contractions), prostaglandins (cervical ripening), and CRH (↑ cortisol, estrogen, surfactant
56
What are the three stages of labour?
Cervical dilation, delivery of baby, delivery of placenta
57
Which hormones prepare the breast for lactation during pregnancy?
Estrogen (ducts), progesterone (alveoli), prolactin (enzymes).
58
What allows milk secretion after birth?
Drop in estrogen and progesterone removes inhibition on prolactin
59
How does breastfeeding suppress ovulation?
Prolactin inhibits GnRH → ↓ FSH and LH → temporary infertility (lactational amenorrhea