what is bronchiolitis
viral infection of the bronchioles
mc causative organism for bronchiolitis
respiratory syncytial virus (RSV)
what age does bronchilotis affect
usually affects children under the age of 2.
mainly in winter and spring months
what physiological changes occur in response to viral infection in the bronchioles
Proliferation of goblet cells causing excess mucus production
IgE-mediated type 1 allergic reaction causing inflammation
Bronchiolar constriction
Infiltration of lymphocytes causing submucosal oedema
Infiltration of cytokines and chemokines
what causes the clinical features present in bronchiolitis
The combination of mucus, oedema and increased cells in the bronchioles leads to a ball-valve effect resulting in hyperinflation, increased airway resistance, atelectasis and ventilation-perfusion mismatc
RF for bronchilotis
Being breast fed for less than 2 months
Smoke exposure
Having siblings who attend nursery or school (increased risk of exposure to viruses)
Chronic lung disease due to prematurity
symptoms of bronchilotis
increasing symptoms over 2-5 days,
Low-grade fever
Nasal congestion
Rhinorrhoea
Cough
Feeding difficulty
clincial findings on examination of bronchilitis
Tachypnoea
Grunting
Nasal flaring
Intercostal, subcostal or supraclavicular recessions
Inspiratory crackles
Expiratory wheeze
Hyperinflated chest
Cyanosis or pallor
ddx for bronchilotis
pneumonia
croup
heart failure
bronchitis
investigations for bronchiolitis
pulse oximetry
Nasopharyngeal aspirate or throat swab for RSV
blood and urine culture
FBC
ABG
Chest x ray
features seen on bronchiolitis chest x ray
Hyperinflation
Focal atelectasis
Air trapping
Flattened diaphragm
Peribronchial cuffing
how to manage bronchiolotis at home
fluids, good nutrition and temperature control
when shpuld urgent hospial referral be made for bronchiolitis
Apnoea
Child looks seriously unwell
Severe respiratory distress eg. grunting, marked recessions, respiratory rate >70
Central cyanosis
Oxygen sats < 92%
treatment of bronchiolitis in hospital
Give oxygen if sats < 92% in room air
Give fluids via nasogastric or orogastric tube if inadequate oral intake
Consider CPAP if there is impending respiratory failure
Perform upper airway suctioning if there are upper airway secretions or apnoea
when should non urgent hospital admission be made for bronchiolitis
Resp Rate > 60
- Clinical dehydration
complications of bronchiolitis
Hypoxia
Dehydration
Fatigue
Respiratory failure
Persistent cough or wheeze
Bronchiolitis obliterans
how long does bronchilotis last
usually lasts 7-10 days
Most children who require hospital admission can cough for up to 6 weeks,
signs of respiratory distress
Raised respiratory rate
Accessory muscle use (e.g., sternocleidomastoid, abdominal and intercostal muscle use)
Intercostal and subcostal recessions
Nasal flaring
Head bobbing
Tracheal tug
Grunting