SAMPLE

Question 1

TRIPTANS QUICK PEARLS
- Quickest onset of actions: _ (SC), sumatriptan and zolmitriptan (NS)
- quickest onset (oral): eletriptan, _, almotriptan, rizatriptan
- longest duration: _, naratriptan
- ODT formulation: _, zolmitriptan

Answer 1

sumatriptan; sumatriptan; frovatriptan; rizatriptan

Question 2

TRIPTANS QUICK PEARLS
DDIs:
_: rizatriptan (5 mg/dose, 15 mg max total)
_: sumatriptan, rizatriptan, zolmitriptan
CYP3A4 inhibs: _ (within 72 hrs of inhibitor)

Answer 2

propranolol; MAOI; eletriptan

Question 3

MIGRAINE
“gepants” CGRP antagonists. All oral except zavegepant (Intranasal):
Acute vs preventative:
- atogepant (QULIPTA) - _
- rimegepant (NURTEC ODT) - _
- ubrogepant (UBRELVY) - _
- zavegepant (ZAVZPRET) - acute only (intranasal)

Answer 3

preventative only; acute and preventative; acute only

Question 4

MIGRAINE
Of the gepants only _ can be repeated in 2 hours _ (UBRELVY)

Answer 4

ubrogepant