What percentage of people who are infected with Tb with and without AIDS develop the disease ?
7-10% develop the disease in their LIFE times
AIDS patients 10% per YEAR will develop the disease
WHo are more likely to progress to active Tb disease?
HIV infected and Recently infected (within the past 2 years)
How is TB transmitted?
airborne
Droplet nucleus-alveolar macrophage access-regional lymph node and blood borne spread
What does the quantiferon assay measure?
the amount of interferon gamma
What tests do you do to diagnose Tb?
2. Sputum nucleic acid amplification testing (NAAT)
How are nontuberculous mycobacteria acquired?
environmental pathogens that affect predisposed hosts
-not contageous
What is a predisposing factor NTM?
structural lung abnormality