the genetic code is share universally by ALOMST all organisms. what are the exceptions?
- ciliates UAA UAG not stop codons
- plastids and mitochondria have their own DNA
- yeast mitochondria CUA -> a different amino acid
how can caner on retinas occur as a transcription error? how is it treated?
retinoblastoma pr- disruption
fails as cycle break -> endless growth leads to retinal cancer
treatment:
chemo
list diseases/conditions related to transcription errors
diabetes
Alzheimer’s
parkinsons
aging
cancer
how are cancer treatments designed knowing that its a transcription related disease?
drugs inhibit enzymes that unwind DNA to prevent transcription
Dr. Juliet Daniel’s research
triple negative breast cancer
KAISO (transcription factor)- regulates gene expression that controls cell growth and cell-cell adhesion. malfunction leads to cancer growth
triple negative tumours lack 3 receptors that can’t be treated with drugs, only chemo
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T1 modules 1+223
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T1 modules 3+414
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Theme 1 Applied Lectures10
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T2 Modules 1+212
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Theme 2 Applied Lectures5
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T2 modules 3+414
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T2 Applied Lecture 20
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T3 module 18
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T3 modules 3: eukaryotic transcriptional regulation7
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T3 applied lectures4
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T3 module 2: prokaryotic transcriptional regulation7
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T4 Module 110
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T4 Module 25
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T4 Module 3 - Applications of DNA replication5
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T4 module 4: DNA mutations7
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T5 module 1: genetic variation5
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T5 module 2: Meiosis6
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T5 module 3: chromosomes + linkage6
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T5 Applied lecture15
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T4 Applied lectures6
