What will happen to all individuals with lethal genes?
They will die before sexual maturity - embryonic, fetal, prenatal and postnatal lethality
Lethal genes
Most are recessive; Lethal in homozygotes, heteros are carriers
Sublethal condition
more than 50% die
Sub vital condition
more than 50% will live but they will have defects
Dominant lethal genes
Lethal White Foal Syndrome (LWFS) in American Paint Horses; Manx tails; Merle colour in dogs
Manx tails
Homozygous for tailessness (MM) are born dead - lethal
Merle colour in dogs
Subcital; 50% will live but will have defects; MM-subvital; Mm - merle colour