Continuous hybridization techniques
crisscross breeding; rotational crossing
Crisscross
breeding of crossebred females to purebred males of two different breeds alternatively using paternal heterosis
Rotational crossing
Three or more breeds; first crossbred females (F1=AB) are AI’d by a purebred male C; The next female generation (R1=ABC) are inseminated by a new purebred male (D); Next female generation (R2=ABCD) are insemintead by A sire; Males and culled females are end product
Recombination losses
loss of heterozygosity due to homologous recombination, one allele variety is lost, can potentially lead to disease development (loss of tumor suppression allele).