central dogma (including transcription and translation)
DNA
transcription
RNA
translation
amino acid chain
folding
protein
biochemistry of DNA (3)
replication
transcription
translation
does protein ever go back to RNA or DNA
no
what polymerase for retroviruses
RdRp (RNA dependent RNA polymerase)
RNA viruses use what sense of RNA to replicate
antisense
whats the right orientation of RNA for protein synthesis
sense RNA
does RNA require DNA do replicate itself
no
enzyme that makes RNA into DNA
retrotranscriptase (RT)
RT reads what sense of RNA
+ sense
why must RNA sometimes become DNA
DNA can integrate into the genome
protein + infection means what
Prion
normal protein beta sheet and a helix breakdown
3%
40%
misfiled proteins become rich in what
beta sheets
are prions self replicable
yes
protein replicating is what
prions
transcription
DNA into RNA
do prokaryotes have compartments
no
mRNA processing
5’ capping
poly A tail polymerization
RNA is synthesized where
nucleus
phages are what
DNA viruses that infect bacteria
how is a prion successful
phage must hijack the bacterial transcriptional and translational machineries
