Type IV

Question 1

Graft vs Host disease

Answer 1

GVHD
- Immune cells present in donor tissue (the graft) attack host’s own tissues

Question 1

Type IV

Answer 1

Delayed hypersensitivity
- Mediated by T cell lymphocytes
> do not involve antibody
- 12-72 hours after exposure to antigen
> EX: TB test, posion ivy, graft vs host

Question 2

Delayed Hypersensitivity - CMs

Answer 2

• Skin rash
• Jaundice
• GI distress

Question 3

Delayed Hypersensitivity - Medications

Answer 3

• Immunosuppressive meds are primary therapy
  > prednisone, cellcept