UC

Question 1

Possible etiology

Answer 1

Autoimmune

Question 2

Location

Answer 2

Colitis: colonic and continuous

always rectal involvement

Question 3

Gross morphology

Answer 3

Mucosal and submucosal inflam only
Fiable mucosal pseudopolyps with free hanging mesentery

Loss of haustra: leadpipe appearance on imaging

Question 4

Microscopic

Answer 4

Crypt abscess and ulcer
Bleeding
No granuloma (TH2 mediated vs. Crohns)

Question 5

Complication

Answer 5

Malnutrition,
Sclerosis cholangitis
Toxic megacolon
Colorectal carcinoma (worse with R sided or pancolitis)

Question 6

Intestinal manifestation

Answer 6

Bloody diarrhea

Question 7

Extraintestinal manifestations

Answer 7

Pyroderma gangrenosum
(vs. erythema nodosom of crohns)
1' scleorsing cholangitis
Ankylosing spondylitis
Uveitis

Question 8

Treatment

Answer 8

ASA prep (sulfasalazine)
6-Mercaptopurine
Infliximab
Colectomy.