- Urticaria is a local or generalised superficial swelling of the skin - Itchy wheals present - It is due to increase in permeability of capillaries and small venules - A large number of inflammatory mediators are activated including prostaglandins, leukotrienes and the major role being histamine derived from skin mast cells.

- Deeper swelling involving the dermis and the subcutaneous tissue: swelling of the tongue and lips

- Bronchospasm, facial and laryngeal oedema, hypotension

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What is Urticaria?

Urticaria is a local or generalised superficial swelling of the skin
Itchy wheals present
It is due to increase in permeability of capillaries and small venules
A large number of inflammatory mediators are activated including prostaglandins, leukotrienes and the major role being histamine derived from skin mast cells.

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What are the causes of Urticaria?

Idiopathic
Food (nuts, sesame seeds, shellfish, dairy)
Drugs (penicillin, NSAIDs, Morphine, ACE, insect bites, contact, viral or parasitic infections, autoimmune and hereditary)

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                    at is the managment for Urticaria?

1st: non-sedating histamines
2nd: Corticosteroids for severe acute urticaria and angioedema

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What is Angioedema?

Deeper swelling involving the dermis and the subcutaneous tissue: swelling of the tongue and lips

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What is the managment for Angioedema?

corticosteroids

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What is anaphylaxis?

Bronchospasm, facial and laryngeal oedema, hypotension

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What is the treatment for anaphylaxis?

`Adrenaline, Corticosteroids and antihistamines

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Urticaria Flashcards

(7 cards)