VIRAL HEPATITIS

Question 1

Viruses causing HEPATITIS

Answer 1

1. HAV
2. HBV
3. HCV
4. HDV
5. HEV

Question 2

Family of Viruses
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Answer 2

Hepatitis A = Picornaviridae Family.
Hepatitis B = Hepadnaviridae Family.
Hepatitisc = Flavivirus.
Hepatitis D = Rna Incomplete Virus.
Hepatitis E = Calcivirus

Question 3

Causes of Acute HEPATITIS

🧠⚡Acute ⚡

Answer 3

1. HEPATITIS A
2. HEPATITIS E

Question 4

Viral Causes of Chronic HEPATITIS
🧠⚡Chronic⚡
🧠⚡+1 & -1 ⚡

Answer 4

HEPATITIS B
HEPATITIS C
HEPATITIS D

Question 5

1. ICOSAHEDRAL SYMMETRY
   ➕
2. DO NOT HAVE ENVELOP
   ➕
3. CAN CAUSE ACUTE LIVER FAILURE
   ➕
4. ROUTE: FECO-ORAL Route

Answer 5

HEPATITIS A & E
Common Features

Question 6

SPHERICAL SYMMETRY
➕
ENVELOPED

Answer 6

HEPATITIS B, C & D
Common Features

Question 7

⚡⚡ MOST COMMON CAUSE of ALF in INDIA

⚡⚡ MOST COMMON CAUSE of ALF in WESTERN Countries

Answer 7

⚡⚡ MOST COMMON CAUSE of ALF in INDIA
🎯 HEPATITIS A & E

⚡⚡ MOST COMMON CAUSE of ALF in WESTERN Countries
🎯 PARACETAMOL Poisoning

Question 8

HEPATITIS A
🧠⚡A ⚡

Answer 8

Asymptomatic
Acute
Alone (NO CARRIERS)

Question 9

⚡⚡ MOST COMMON CAUSE of ACUTE RELAPSING VIRAL HEPATITIS

Answer 9

HEPATITIS A

Question 10

All viral Hepatitis have ssRNA, except

Answer 10

HEPATITIS B (dsDNA)

Question 11

Incubation periods of HEPATITIS Virus

Answer 11

HEPATITIS A: 4 weeks (30 days)
HEPATITIS E: 40 days

Question 12

Extra-Hepatic Manifestations of HAV
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Answer 12

1. Arthritis
2. Adult onset Still’s syndrome
3. Aplastic Anemia
4. ATN
5. Polymyositis
6. Rhabdomyolysis
7. Interstitial Nephritis

Question 13

Serology of HEPATITIS A

Answer 13

Question 14

Anti-HAV IgM coverts to IgA after

Answer 14

12 weeks

Question 15

💊💉 MANAGEMENT of HEPATITIS A

Answer 15

1. Hydration
2. Glucose replenishment: 3 points of 10% DEXTROSE

Question 16

Hepatitis A Vaccine

Answer 16

HAV-RIX Vaccine
Adult: 1 ml IM DELTOID
2DOSES (0, 6-12months)

Children: 0.5 ml IM

Question 17

PRE-EXPOSURE Prophylaxis of HEPATITIS A

Answer 17

> 2 weeks PRIOR to Travel

Question 18

POST-EXPOSURE Prophylaxis of HEPATITIS A

Answer 18

Within 2 weeks of Exposure
➕
HAV Ig

Question 19

⚡⚡ MOST COMMON GENOTYPE OF HEPATITIS A in INDIA

⚡⚡ MOST COMMON GENOTYPE OF HEPATITIS E in INDIA

Answer 19

Both GENOTYPE 1

Question 20

Difference BETWEEN HAV & HEV

Answer 20

Question 21

💊💉 MANAGEMENT of ACUTE LIVER FAILURE with HEV

Answer 21

Ribaverin ± PEG-IFN-Alpha

Question 22

SEROLOGY of HEPATITIS E

Answer 22

Anti-HEV IgM: ACUTE INFECTION
Anti-HEV IgG: Remote Infection