Vitamin
Substance essential for the maintenance of normal metabolic functions, but is not made in the body therefore must be provided from outside sources
Water-soluble
Vitamin C and eleven vitamins in the B group are water-soluble
Fat-soluble
Vitamins, A, D, E, and K are fat soluble
Vitamin supplementation reason for use
Need for increased nutrition, absorbance disturbances, inadequate nutritional intake
Nutritional Approach to Vitamin therapy
Individuals select a diet adhering to RDA (recommended dietary allowances)
Megavitamin Approach to Vitamin Therapy
Individuals ingest vitamins in excess of the RDA
Vitamin A
Found in animal products such as liver, milk fat, egg yolk
Function: growth and development for normal structure especially mucous membranes and epithelial cells, and as a constituent of a complex in the eyes (rhodopsin)
Vitamin A Uses and Effects
Therapeutic uses: infancy, pregnancy, lactation
Deficiency: delay of growth and development, night blindness, eye dryness, changes in cells lining the bronchioles in the lungs
Excessive Intake: itchy skin, vomiting, headache, enlarged liver and spleen
Retinoids
Associated with damage to unborn children, depression, diabetes, liver disease
Vitamin D
Found in meat, fish, mushrooms
Function: increase absorption of calcium and phosphate from intestine needed for new bone formation, regulates blood calcium level and removal of calcium from older bones
Vitamin D Uses and Effects
Therapeutic Uses: used in prevention of osteoporosis
Deficiency: decreased absorption of calcium and phosphate from intestine and therefore decreased blood calcium level can lead to bowleggedness and rickets
Excessive Intake: removal of calcium from bone, fatigue, nausea, vomiting, diarrhea impaired kidney function
Vitamin E
Found in vegetable oils and leafy greens
Function: antioxidant, protects cells in cardiovascular system
Vitamin E Uses and Effects
Therapeutic Uses: hemolytic anemia
Deficiency: rare, may occur in people with malabsorption syndrome
Excessive Intake: inhibits platelet aggregation and contribute to the anticoagulant effect of warfarin
Vitamin B12 and Folic Acid
Found mainly in meats, mushrooms, and dairy products
Function: work together to synthesis of red blood cells
Vitamin B12 and Folic Acid Uses and Effects
Therapeutic Use: absorption decreases with age, folic acid prevents neural tube defects
Deficiency: pernicious anemia
Excessive Intake: no toxic effects
Vitamin C
Found in fruits and vegetables
Function: holds cells together, required for formation of bone and teeth, functions as an antioxidant, helps absorbs iron
Vitamin C Uses and Effects
Therapeutic Effects: prevention and treatment of scurvy
Deficiency: can result in scurvy
Excessive Intake: diarrhea, formation of kidney stones, rebound scurvy