Week 1 - Study Guide Questions

Question 1

what is contact inhibition

Answer 1

• this is one of the ways that cellular proliferation is controlled
• normal cells respect the boundaries of the cells surrounding them & will not invade territory that is not their own
• cancer cells lack contact inhibition & will grow on top of other cells

Question 2

what is proliferation

Answer 2

• cell growth & division

Question 3

what is differentiation

Answer 3

• an orderly process where the cell progresses from a state of immaturity to a state of maturity
• kinda like specialization

Question 4

define malignant

Answer 4

• cancerous
• cells with invasive and metastatic potential
• cells are poorly differentiated

Question 5

define neoplasm

Answer 5

• tumour

- abnormal mass of cells which grow & divide without response to normal regulatory controls

Question 6

define benign

Answer 6

• a tumour with limited potential for growth and metastasis
• cells are well differentiated
• non cancerous

Question 7

define carcinogen

Answer 7

• cancer-causing agents that are capable of causing cellular alteration

Question 8

define pancytopenia

Answer 8

• low levels of RBC, WBC, and platelets

Question 9

what are colony stimulating factors?

Answer 9

• family of glycoproteins produced by various cells

Question 10

what is the function of colony stimulating factors

Answer 10

• stimulate production, maturation, regulation, and activation of cells of the hematological system

Question 11

what is radiation theraoy

Answer 11

• local treatment for cancer

Question 12

in what situations would chemotherapy be utilized?

Answer 12

• when the cancer is disemmiated/systemic

Question 13

what is the main goal of radiation therapy?

Answer 13

• cure, control, and palliation

Question 14

list 3 differences between radiation & chemo in terms of their effect on the body & cells

Answer 14

1. admin of radiation results in limited ability to normal cells to recover from damange & potential irreversible effects = ex. hair will not grow back but will in chemo
2. in radiation, only cells in the radiation field will be affected by treatment. in cancer, it is systemic
   3.

Question 15

in what situations would radiation be used?

Answer 15

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