3. RA Flashcards

(11 cards)

1
Q

(RA)

Hauptrisikofaktor

A

Rauchen

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2
Q

(RA)

Sonderformen
(Komplikationen)

A

Zervikalarthritis
- zervikale Myelopathie
- atlantoaxiale Instabilität

Felty-Syndrom
- Granulozytopenie
- Splenomegalie

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3
Q

(RA)

ACR/EULAR Klassifikationskriterien

A
  1. geschwollene/schmerzhafte Gelenke
  2. Serologie
    (RF/anti-CCP)
  3. Entzündungsparameter
    (CRP/BSG)
  4. Symptomdauer
    (> 6 Wochen)
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4
Q

(RA)

Serologie: Spezifität

A
  • RF: niedrige
  • anti-CCP: sehr hohe
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5
Q

(RA)

Leitsymptome

A
  • symmetrische erosive Polyarthritis kleiner Gelenke
  • Morgensteifigkeit > 60 min
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6
Q

(RA)

Prädilektionsstellen

A
  1. MCP
  2. Hand
  3. PIP
  4. Knie
  5. MTP
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7
Q

(RA)

andere Symptome

A
  1. Bursitis
  2. Lungenbeteiligung
  3. sekundäres Sjögren-Syndrom
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8
Q

(RA)

Befunde

A

Rheumaknoten

Deformitäten
- 90-90
- Knopfloch
- Schwanenhals

Gaenslen-Zeichen
- Kompressionsschmerz auf MCP-Gelenke

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9
Q

(RA)

Laborbefunde

A
  • ↑ Ferritin
  • ↑ CRP/BSG
  • (+) RF/anti-CCP
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10
Q

(RA)

Bildgebungen
(Befunde)

A
  • Frühstadium: MRT
    (synoviale Hyperplasie)
  • Spätstadium: Röntgen
    (Erosionen)
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11
Q

(RA)

Therapie

A
  1. Prednison ≤ 5 mg/d p.o. für 3-6 Monate
    + csDMARD (MTX 10-25 mg p.o. 1x/Woche)
  2. +bDMARD (TNF-Inhibitoren) /
    tsDMARD (JAK-Inhibitoren)
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