absorption of water soluble vitamins occurs via
Na+- dependent cotransport
small intestine
absorption of B12 requies
Intrinsic factors (released from Parietal cells)
first step of vit B12 absorption
vit B12 is released from food by the digestive action of Pepsin in stomach
second step of vit B12 absorption
free vit B12 binds R proteins
where does the R protein come from?
the salivary jucies
third step of vit B12 absorption
in duodenum, pancreatic protease degrade R protein -> vit B12 transfered to IF
fourth step of vit B12 absorption
vit B12- IF complex travels to ilium -> being absorbed